Controlled - Release of Oral Dosage Forms
نویسنده
چکیده
Formulation, Fill & Finish 2003 10 he technologies behind oral drug delivery have emerged from the mainstream pharmaceutical industry and have become influential forces in their own right, as evidenced by the burgeoning “drug delivery companies” that are at the forefront of innovation and hold their own niche market. Drug delivery companies and their pharmaceutical industry partners are poised to reap the rewards of the multibillion-dollar drug delivery market, which is forecast to grow to about $70 billion by 2005 (1). The market for oral controlled drug delivery alone is expected to grow at 9% or more every year through 2007. The driving forces behind this booming market can be divided into two main groups: patient-related factors (see Table I and Figure 1) and market-driven factors.
منابع مشابه
Matrix Tablets: An Effective Way for Oral Controlled Release Drug Delivery
The purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. Matrix system was the earliest oral extended release platform for medicinal use. Matrix tablets are most commonly used methods to modulate the release profile of drugs. They are much desirable and preferred for such therapy because they o...
متن کاملHydrodynamically Balanced Gastro-Retentive Site Specific Drug Delivery System: An Innovative Approach
Conventional oral dosage forms suffer with many disadvantages. To avoid such limitations controlled release dosage forms are preferred. When these controlled release dosage forms administered by oral route retained in the stomach and release the drug in a controlled fashion continuously in gastrointestinal tract [1]. Controlled release systems also suffer with some limitations such as short gas...
متن کاملGuidelines for the Design and Evaluation of Oral Prolonged Release Dosage Forms
In recent years, in association with progress and innovation in the field of pharmaceutical technology, there has been an increasing effort to develop prolonged release dosage forms for many drugs. Correspondingly, a growing number of new prolonged release dosage forms have been submitted for regulatory approval. Prolonged release dosage forms have many advantages in safety and efficacy over im...
متن کاملAdvances in oral transmucosal drug delivery.
The successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity. Oral transmucosal delivery, especially buccal and sublingual delivery, has progressed far beyond the use of traditional dosage forms with novel approaches emerging continuously. This review highlights the physiological challenges as well as the advances and opportunities fo...
متن کاملPreparation and Evaluation of Sustained Release Microsphere of Norfloxacin Using Sodium Alginate
Oral controlled drug delivery systems represent the most popular form of sustained drug delivery systems for the obvious advantages of oral route of drug administration. Such systems release the drug with constant or variable release rates. The oral controlled release systems shows a typical pattern of drug release in which the drug concentration is maintained in the therapeutic window for a pr...
متن کاملControlled Release Suspension: a Review
Oral drug delivery is most preferred route of drug delivery. Novel technologies with improved performance, patient compliance, and enhanced quality have emerged in the recent past. Sustained release dosage forms aimed at controlling the rate of release as well as maintaining desire drug level in the blood for long duration. An oral suspension could be the best suitable dosage form for geriatric...
متن کامل